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Líneas de investigación:

Hepatocarcinoma.
Metabolómica.
Esteatosis.
Inmunosupresión en trasplante hepático.
Eficacia del trasplante hepático en indicaciones límites.
Donantes en el trasplante hepático.
Marcadores tumorales en metástasis hepáticas de carcinoma colorectal.

Actividades del grupo:

Marcadores metabolómicos en la evaluación de la respuesta al sorafenib en los pacientes con hepatocarcinoma avanzado.

Desde 2007 los pacientes con hepatocarcinoma avanzado y buena función hepática son tratados con sorafenib, un inhibidor de tirosinkinasa que ha demostrado aumentar la supervivencia. Sin embargo, debido a su mecanismo de acción, los criterios radiológicos convencionales no son útiles para evaluar la respuesta al tratamiento con sorafenib. Teniendo en cuenta que se trata de un fármaco con un modesto beneficio de supervivencia, efectos adversos relevantes y alto coste sería importante disponer de algún marcador biológico para evaluar la respuesta terapéutica. Debido a su mecanismo de acción antiproliferativo y antiangiogénico es posible que la metabolómica, por su capacidad para identificar miles de moléculas que reflejan procesos intracelulares, pueda identificar algún marcador pronóstico y/o de respuesta.

Validación clínica de un test no invasivo para el diagnostico diferencial precoz entre esteatosis simple y esteatohepatitis.

 

Respecto a la inmunosupresión en el trasplante hepático, nuestra actividad se centra en:

Estudio de eficacia-seguridad de fármacos inmunosupresores en el trasplante hepático. En este campo participamos en estudios multicéntricos en Fase II y III de nuevos fármacos inmunosupresores.
Desarrollo de un modelo farmacocinético poblacional que permita una mejor dosificación del fármaco inmunosupresor principal (tacrolimus), con mayor eficacia y con los menores efectos secundarios, en colaboración con el Grupo de Farmacocinética Clínica del Departamento de Farmacología de la Universidad del País Vasco.
Estudio de los distintos polimorfismos genéticos de enzimas metabolizadores (fundamentalmente CYP y p-glicoproteina) en el hígado y en el intestino, que podrían determinar cambios en la eficacia y toxicidad del tacrolimus, en colaboración con Dynakin, Progenika y el Grupo de Farmacocinética Clínica del Departamento de Farmacología de la Universidad del País Vasco.
Por otro lado, participamos en estudios multicéntricos para evaluar la eficacia del trasplante hepático en indicaciones límite, tales como VIH, tumores hepáticos y en estudios sobre factores de riesgo del donante y en un modelo de asignación donante –receptor con criterios expandidos.

Respecto a la cirugía hepatobiliar, estamos realizando estudios de marcadores tumorales en metástasis hepáticas de carcinoma colorectal en colaboración con Pharmakine y BIOEF.

Coordinador/a del grupo:

Integrantes del grupo:

Publicaciones del grupo:

Cuervas-Mons, V, Manuel Sousa, J., Serrano, T., Ignacio Herrero, J., Jimenez, M., Gimenez, C., Del Campo, S., Esteban-Mur, I, J., Crespo, G., Moreno, A., de la Rosa, G., Rimola, A., Miro, J. M., Suarez, F., Castro, M. A., Lopez, S., Pedreira, J. D., Vazquez, P., Aguero, F., Blanch, J., Brunet, M., Calatayud, D., Cervera, C., de Lazzari, E., Fondevila, C., Forner, A., Fuster, J., Forns, X., Gil, A., Gatell, J. M., Laguno, M., Lligona, A., Mallolas, J., Murillas, J., Navasa, M., Paredes, D., Perez, I, Torres, F., Tural, C., Tuset, M., Antela, A., Losada, E., Molina, E., Otero, E., Varo, E., Araiz, J. J., Barrao, E., Larraga, J., Letona, S., Lozano, R., Luque, P., Navarro, A., Sanjoaquin, I, Tejero, E., Banares, R., Berenguer, J., Clemente, G., Cosin, J., Ferreiroa, J. P., Garcia-Sabrido, J. L., Gutierrez, I, Lopez, J. C., Miralles, P., Ramirez, M., Rincon, D., Sanchez, M., de la Cruz, J., Fernandez, J. L., Lozano, J. M., Santoyo, J., Rodrigo, J. M., Suarez, M. A., Rodriguez, M., Alonso, M. P., Asensi, V, Gonzalez-Pinto, I, Rafecas, A., Baliellas, C., Carratala, J., Fabregat, J., Fernandez, N., Jorba, R., Llado, L., Montejo, M., Bustamante, J., Fernandez, J. R., Gastaca, M., Gonzalez, J., Montejo, E., Ortiz de Urbina, J., Ruiz, P., Suarez, M. J., Valdivieso, A., Ventoso, A., Abradelo, M., Calvo, J., Costa, J. R., Garcia-Sesma, A., Jimenez, C., Manrique, A., Meneu, J. C., Moreno, E., Moreno, V, Olivares, S. P., Pulido, F., Rubio, R., Blanes, M., Berenguer, M., Lopez, J., Lopez, R., Prieto, M., Farinas, M. C., Casafont, F., Echevarria, S., Fabrega, E., Gomez-Fleitas, M., Arminanzas, C., Herrera-Norena, J. L., Moreno, S., Barcena, R., Fortun, J., Moreno, A. M., Martin-Davila, P., Torre-Cisneros, J., Barrera, P., Briceno, J., Caston, J. J., Costan, G., de la Mata, M., Lara, R., Lopez-Cillero, P., Rivero, A., Rufian, S., Sanchez-Antolin, G., Garcia Pajares, F., Bachiller, P., Almohalla, C., Barrera, A., Conde, R., Bilbao, I, Campos-Varela, I, Charco, R., Esteban, I, J., Gavalda, J., Len, O., Pahissa, A., Ribera, E., Vargas, V., Pons, J. A., Cordero, E., Bernal, C., Cisneros, J. M., Gomez, M. A., Pascasio, J. M., Rodriguez, M. J., Sayago, M., Suarez, G., Gonzalez-Garcia, J., Aznar, E., Esteban, H., Moyano, B., Garrido, G., Mahillo, B., Matesanz, R., Guerra, L., Manzanera, M., Samuel, D., FIPSE LT-HIV Investigators. Direct-acting antivirals are effective and safe in HCV/HIV-coinfected liver transplant recipients who experience recurrence of hepatitis C: A prospective nationwide cohort study (vol 18, pg 2513, 2018). Am. J. Transplant.. 2019; 19(2): 614 - 614. FI: 7,163(Q1). DOI: 10.1111/ajt.15244.

Fernandez Cepedal, Lara, Gastaca Mateo, Mikel, Prieto Calvo, Mikel, Valdivieso Lopez, Andres, Gomez Cruzado, Laura Fernandez, Perez Gonzalez, Christian, Perfecto Valero, Arkaitz, Colina Alonso, Alberto. Liver transplantation following hepatic artery avulsion in a trauma patient. J. Surg. Case Rep.. 2019; 2019(4): rjz063. FI: (Q). DOI: 10.1093/jscr/rjz063.

Hessheimer, Amelia J., Coll, Elisabeth, Torres, Ferran, Ruiz, Patricia , Gastaca, Mikel , Ignacio Rivas, Jose, Gomez, Manuel, Sanchez, Belinda, Santoyo, Julio, Ramirez, Pablo, Parrilla, Pascual, Miguel Marin, Luis, Angel Gomez-Bravo, Miguel, Carlos Garcia-Valdecasas, Juan, Lopez-Monclus, Javier, Bosca, Andrea, Lopez-Andujar, Rafael, Fundora-Suarez, Jiliam, Villar, Jesus, Garcia-Sesma, Alvaro, Jimenez, Carlos, Rodriguez-Laiz, Gonzalo, Llado, Laura, Carlos Rodriguez, Juan, Barrera, Manuel, Charco, Ramon, Angel Lopez-Baena, Jose, Briceno, Javier, Pardo, Fernando, Blanco, Gerardo, Pacheco, David, Dominguez-Gil, Beatriz, Sanchez Turrion, Victor, Fondevila, Constantino. Normothermic regional perfusion vs. super-rapid recovery in controlled donation after circulatory death liver transplantation. J Hepatol. 2019; 70(4): 658 - 665. FI: 18,946(Q1). DOI: 10.1016/j.jhep.2018.12.013.

Ruiz, Patricia , Gastaca, Mikel , Javier Bustamante, Francisco, Ventoso, Alberto, Palomares, Ibone, Prieto, Mikel, Ramon Fernandez, Jose, Salvador, Patricia, Ignacio Pijoan, Jose, Valdivieso, Andres. Favorable Outcomes After Liver Transplantation With Normothermic Regional Perfusion From Donors After Circulatory Death: A Single-center Experience. Transplantation. 2019; 103(5): 938 - 943. FI: 4,593(Q1). DOI: 10.1097/TP.0000000000002391.

Perfecto Valero, Arkaitz, Serrano Hermosilla, Clara, Correa Zapata, Jenny Catalina, Prieto Calvo, Mikel. Radiopaque artifact in a liver segment. Angiologia. 2019; 71(3): 119 - 120. FI: (Q). DOI: 10.20960/angiologia.00005.

Hessheimer, Amelia J., Coll, Elisabeth, Ruiz, Patricia , Gastaca, Mikel , Ignacio Rivas, Jose, Gomez, Manuel, Sanchez, Belinda, Santoyo, Julio, Ramirez, Pablo, Parrilla, Pascual, Miguel Marin, Luis, Angel Gomez-Bravo, Miguel, Carlos Garcia-Valdecasas, Juan, Lopez-Monclus, Javier, Bosca, Andrea, Lopez-Andujar, Rafael, Fundora-Suarez, Jiliam, Villar, Jesus, Garcia-Sesma, Alvaro, Jimenez, Carlos, Rodriguez-Laiz, Gonzalo, Llado, Laura, Carlos Rodriguez, Juan, Barrera, Manuel, Charco, Ramon, Angel Lopez-Baena, Jose, Briceno, Javier, Pardo, Fernando, Blanco, Gerardo, Pacheco, David, Dominguez-Gil, Beatriz, Sanchez Turrion, Victor, Fondevila, Constantino. The UK DCD Risk Score: Still no consensus on futility in DCD liver transplantation. J Hepatol. 2019; 70(5): 1034 - 1035. FI: 18,946(Q1). DOI: 10.1016/j.jhep.2019.01.004.

Hessheimer, Amelia J., Coll, Elisabeth, Ruiz, Patricia , Gastaca, Mikel , Ignacio Rivas, Jose, Gomez, Manuel, Sanchez, Belinda, Santoyo, Julio, Ramirez, Pablo, Parrilla, Pascual, Miguel Marin, Luis, Angel Gomez-Bravo, Miguel, Carlos Garcia-Valdecasas, Juan, Lopez-Monclus, Javier, Bosca, Andrea, Lopez-Andujar, Rafael, Fundora-Suarez, Yiliam, Villar, Jesus, Garcia-Sesma, Alvaro, Jimenez, Carlos, Rodriguez-Laiz, Gonzalo, Llado, Laura, Carlos Rodriguez, Juan, Barrera, Manuel, Charco, Ramon, Angel Lopez-Baena, Jose, Briceno, Javier, Pardo, Fernando, Blanco, Gerardo, Pacheco, David, Dominguez-Gil, Beatriz, Sanchez Turrion, Victor, Fondevila, Constantino. Reply to: ``ormothermic regional perfusion - What is the benefit?''. J Hepatol. 2019; 71(2): 443 - 445. FI: 18,946(Q1). DOI: 10.1016/j.jhep.2019.04.005.

Nevares Herrero, M., Minguez Gabina, P., Esteban Figueruelo, A., Valverde Jorge, R., Fernandez Tercero, I., Ortiz de Zarate, E. Rodeno, Prieto Calvo, M., Valdivieso Lopez, A.. Initial Evaluation of the Protocol to Assess the Function of Future Remnant Liver After Major Hepatectomy by Means of Hepatobiliary Scintigraphy and SPECT/CT Imaging with 99mTc-Mebrofenin. Eur J Nucl Med Mol Imaging. 2019; 46(SUPPL 1): 246 - 247. FI: 7,182(Q1). DOI: .

Prieto Calvo, Mikel, Gastaca, Mikel , Ruiz, Patricia , Ventoso, Alberto, Palomares, Ibone, Valdivieso, Andres. IMPACT OF DONOR AGE ON RECIPIENT RECURRENCE RATE AND SURVIVAL IN LIVER TRANSPLANTATION DUE TO HEPATOCARCINOMA. Transpl. Int.. 2019; 32: 321 - 321. FI: 3,526(Q1). DOI: .

Minambres, Eduardo, Ruiz, Patricia , Angeles Ballesteros, Maria, Sanchez, Laura, Atutxa, Lander, Fernandez-Santiago, Roberto, Manuel Cifrian, Jose, Ventoso, Alberto, Gastaca, Mikel. COMBINED LUNGS AND LIVER PROCUREMENT IN CONTROLLED DONATION AFTER CIRCULATORY DEATH USING NORMOTHERMIC ABDOMINAL PERFUSION. INITIAL EXPERIENCE IN TWO SPANISH CENTERS. Transpl. Int.. 2019; 32: 407 - 408. FI: 3,526(Q1). DOI: .

Bustamante, Javier, Arretxe, Enara, Gastaca, Mikel , Alonso, Cristina, Senosiain, Maria, Salvador, Patricia, Ruiz Ordorica, Patricia, Fernandez Ramos, Jose Ramon, Testillano Tarrero, Milagros, Ventoso, Alberto, Palomares, Ibone, Prieto, Mikel, Coya, Raquel, Valdivieso, Andres, Suarez Regueiro, Maria Jesus. METABOLOMIC CHARACTERIZATION OF VERY EARLY HEPATOCELLULAR CARCINOMA IN CIRRHOTIC PATIENTS SUBMITTED FOR LIVER TRANSPLANTATION. Hepatology. 2019; 70(1): 1195 - 1195. FI: 14,971(Q1). DOI: .

Rodriguez de Santiago, Enrique, Burgos-Santamaria, Diego, Perez-Carazo, Leticia, Brullet, Enric, Ciriano, Lucia, Riu Pons, Faust, de Jorge Turrion, Miguel Angel, Prados, Susana, Perez-Corte, Daniel, Becerro-Gonzalez, Irene, Martinez-Moneo, Emma, Barturen, Angel, Fernandez-Urien, Ignacio, Lopez-Serrano, Antonio, Ferre-Aracil, Carlos, Lopez-Ibanez, Maria, Carbonell, Carlos, Nogales, Oscar, Martinez-Bauer, Eva, Teran Lantaron, Alvaro, Pagano, Giulia, Vazquez-Sequeiros, Enrique, Albillos, Agustin, Guerrero Garcia, Antonio, Volpato, Nadja, Rodriguez-Escaja, Carlos, Javier Garcia-Alonso, Francisco, Sevilla-Ribota, Sergio, Marcos Prieto, Hector Miguel, Miguel Chavarria-Herbozo, Carlos, Murcia, Oscar, Aranda-Hernandez, Javier, Borobia, Rodrigo, Lledo, Javier Garcia, Santander, Cecilio, Coto, David, Oyon, Daniel, Ortiz Polo, Inmaculada, Gonzalez-Haba Ruiz, Mariano, Froilan Torres, Consuelo, De Benito Sanz, Marina, Penas, Beatriz, Parejo, Sofia, Juzgado, Diego, Ibanez, Alberto, TC-325 Collaboration Project, Spanish Assoc Gastroenterology. Hemostatic spray powder TC-325 for GI bleeding in a nationwide study: survival and predictors of failure via competing risks analysis. Gastrointest. Endosc.. 2019; 90(4): 581 - 581. FI: 7,229(Q1). DOI: 10.1016/j.gie.2019.06.008.

Prieto M, Gastaca M, Ruiz P, Ventoso A, Palomares I, Perfecto A, Valdivieso A. Long term recurrence free survival in a stage IV gallbladder cancer treated with chemotherapy plus trastuzumab and salvage liver resection.. Ann Hepatobiliary Pancreat Surg. 2019; 23(4): 403 - 407. FI: (Q). DOI: 10.14701/ahbps.2019.23.4.403.

Rystedt, Jenny M. L., Kleeff, Joerg, Salvia, Roberto, Besselink, Mark G., Prasad, Raj, Lesurtel, Mickael, Sturesson, Christian, Abu Hilal, M., Aljaiuossi, A., Antonucci, A., Ardito, F., Ausania, F., Bernon, M., Berrevoet, F., Bjornsson, B., Bonsing, B. A., Boonstra, E. A., Bracke, B., Brusadin, R., Burda, L., Caraballo, M., Casellas-Robert, M., Coker, A., Davide, J., De Gelder, A., De Rose, A. M., Djokic, M., Dudek, K., Ekmekcigil, E., Filauro, M., Fulop, A., Gallagher, T. K., Gastaca, M., Gefen, R., Giuliante, F., Habibeh, H., Halle-Smith, J., Haraldsdottir, K. H., Hartman, V, Hauer, A., Hemmingsson, O., Hoskovec, D., Isaksson, B., Jonas, E., A, Khalaileh, Klug, R., Krige, J., Lignier, D., Lindemann, J., Lopez-Lopez, V, Lucidi, V, Mabrut, J-Y, Mansson, C., Mieog, S., Mirza, D. F., Oldhafer, K. J., Omoshoro-Jones, J. A. O., Ortega-Torrecilla, N., Otto, W., Panaro, F., Pando, E., Paterna-Lopez, S., Pekmezci, S., Pesce, A., Porte, R. J., Poves, I, Prieto Calvo, M., Primavesi, F., Puleo, S., Recordare, A., Rizell, M., Roberts, K., Robles-Campos, R., Sanchiz-Cardenas, E., Sandstrom, P., Saribeyoglu, K., Schauer, M., Schreuder, M., Siriwardena, A. K., Smith, M. D., Silva, Sousa D., Sparrelid, E., Staettner, S., Stavrou, G. A., Straka, M., Stromberg, C., Sutcliffe, R. P., Szijarto, A., Taflin, H., Trotovsek, B., van Gulik, T., Wallach, N., Zieniewicz, K., European-African HepatoPancreato. Post cholecystectomy bile duct injury: early, intermediate or late repair with hepaticojejunostomy - an E-AHPBA multi-center study. HPB. 2019; 21(12): 1641 - 1647. FI: 3,047(Q1). DOI: 10.1016/j.hpb.2019.04.003.

Blanco Fernandez, Gerardo, Gomez Bravo, Miguel Angel, Briceno Delgado, Javier, Valdivieso Lopez, Andres, Lopez-Guerra, Diego, Rodriguez-Laiz, Gonzalo, Villar-del-Moral, Jesus, Pardo Sanchez, Fernando, Santoyo, Julio, Lopez Andujar, Rafael, Nuno, Javier, Sanchez Turrion, Victor, Gonzalez Pinto, Ignacio, Jimenez, Carlos, Lopez Baena, Jose Angel, Gomez Gutierrez, Manuel, Fabregat Prous, Joan, Pacheco Sanchez, David, Barrera, Manuel, Garcia-Gil, Agustin, Ramirez, Pablo, Varo, Evaristo, Bilbao, Itxarone, Fondevila, Constantino, Carlos Rodriguez-Sanjuan, Juan, Grp Espanol Trabajo Trasplante Hep. A survey of Heads of Surgery and Residents on accessibility and employment in liver transplant teams in Spain. Cir. Esp.. 2019; 97(10): 560 - 567. FI: 0,835(Q4). DOI: 10.1016/j.ciresp.2019.03.018.

Ruiz P, Gastaca M, Bustamante FJ, Valdivieso A. The Authors' Reply: To NRP or Not to NRP, That Is the Question….. Transplantation. 2019; 103(12): 400 - 400. FI: 4,593(Q1). DOI: 10.1097/TP.0000000000002878.

Adam R, Karam V, Cailliez V, Grady JGO, Mirza D, Cherqui D, et al. 2018 Annual Report of the European Liver Transplant Registry (ELTR)-50-year evolution of liver transplantation. Transpl. Int. 2018; 31(12): 1293 - 1317. FI: 3,196(Q1). DOI: 10.1111/tri.13358.

Perfecto-Valeroa A, Gastaca-Mateo MA, Prieto-Calvo M, Ortiz-de Urbina J, Valdivieso-Lopez A. Biliary cyst of the cystic duct: A case of Todani type VI. Cir Esp. 2018; 96(10): 658 - 660. FI: 0,841(Q4). DOI: 10.1016/j.ciresp.2018.04.013. EDITORIAL MATERIAL.

Fernández-Gomez L, Prieto-Calvo M, Alonso-Calderon E, Larrea-Oleaga J, Marquina-Tobalina T. Conservative Management of Massive Pneumoperitoneum After Argon Plasma Coagulation. Cir Esp. 2018; 96(1): 56 - 58. FI: 0,841(Q4). EDITORIAL MATERIAL.

Perez-Gonzalez C, Alosno-Calderon E, Sarriugarte-Lasarte A, Mifsut-Porcel P, Prieto-Calvo M. De Garengeot's hernia: report of two cases of this rare entity. Rev. Hispanoam. Hernia. 2018; 6(3): 141 - 144. FI: (Q). DOI: 10.20960/rhh.130.

Manzardo C, Londono MC, Castells L, Testillano M, Montero JL, Penafiel J, et al. Direct-acting antivirals are effective and safe in HCV/HIV-coinfected liver transplant recipients who experience recurrence of hepatitis C: A prospective nationwide cohort study. Am. J. Transplant. 2018; 18(10): 2513 - 2522. FI: 6,493(Q1). DOI: 10.1111/ajt.14996.

Moran RA, Garcia-Rayado G, de la Iglesia-Garcia D, Martinez-Moneo E, Fort-Martorell E, Lauret-Brana E, et al. Influence of age, body mass index and comorbidity on major outcomes in acute pancreatitis, a prospective nation-wide multicentre study. United Eur. Gastroenterol. J. 2018; 6(10): 1508 - 1518. FI: 3,477(Q2). DOI: 10.1177/2050640618798155.

Gastaca M, Bruno M, Ruiz P, Ventoso A, Palomares I, Prieto M, et al. Liver transplantation in patients with espontaneous spleno-renal shunt. Transplantation. 2018; 102(5): 175 - 176. MEETING ABSTRACT.

Gastaca M, Bruno M, Ruiz P, Ventoso A, Palomares I, Prieto M, et al. Liver Transplantation in Patients with Spontaneous Spleno-Renal Shunt. Am. J. Transplant. 2018; 18: 559 - 559. MEETING ABSTRACT

Gastaca M, Bustamante J, Ventoso A, Fernandez JR, Ruiz P, Palomares I, et al. Long-term outcomes of liver transplantation in patients with pre-transplant renal dysfunction treated with induction therapy and delayed reduced de novo once-daily tacrolimus. Transplantation. 2018; 102(5): 247 - 247. MEETING ABSTRACT.

Gastaca M, Bustamante J, Ventoso A, Fernandez J, Ruiz P, Testillano M, et al. Long-Term Outcomes of Liver Transplantation in Patients with Pre-Transplant Renal Dysfunction Treated with Induction Therapy and Delayed Reduced De Novo Once-Daily Tacrolimus. Am. J. Transplant .2018; 18: 838 - 838. MEETING ABSTRACT

Lapitz A, Arbelaiz A, Azkargorta M, Krawczyk M, Santos-Laso A, Perugorria MJ, et al. Novel protein biomarkers in serum extracellular vesicles for the diagnosis of primary sclerosing cholangitis (PSC) in patients with ulcerative colitis (UC). J Hepatol. 2018; 68: 220 - 220. MEETING ABSTRACT.

Herrero JI, Cuervas-Mons V, Gomez-Bravo MA, Fabregat J, Otero A, Bilbao I, et al. Prevalence and progression of chronic kidney disease after liver transplant: a prospective, real-life, observational, two-year multicenter study. Rev. Esp. Enferm. Dig. 2018; 110(9): 538 - 543. FI: 1,632(Q4). DOI: 10.17235/reed.2018.5431/2017.

Sallinen VJ, Le Large TTY, Tieftrunk E, Galeev S, Kovalenko Z, Haugvik SP, et al. Prognosis of sporadic resected small (<= 2 cm) nonfunctional pancreatic neuroendocrine tumors - a multi-institutional study. HPB. 2018; 20(3): 251 - 259. FI: 3,131(Q1). DOI: 10.1016/j.hpb.2017.08.034.

Arbelaiz A, Lapitz A, Krawczyk M, Santos-Laso A, Lavin JL, Perugorria MJ, et al. Serum and urine extracellular vesicles contain mRNA biomarkers for primary sclerosing cholangitis (PSC) and cholangiocarcinoma (CCA). J Hepatol. 2018; 68: 435 - 435. MEETING ABSTRACT.

Gastaca M, Prieto M, Palomares I, Valdivieso A. Significance of measured intraoperative portal vein flows after thrombendvenectomy in deceased donor liver transplantations with portal vein thrombosis. Liver Transplant. 2018; 24(4): 565 - 566. FI: 3,752(Q1). DOI: 10.1002/lt.24996. LETTER.

Hessheimer A, Coll E, Valdivieso A, Gomez M, Santoyo J, Ramirez P, et al. Superior Outcomes Using Normothermic Regional Perfusion in CDCD Liver Transplantation. Transplantation. 2018; 102(7): 380 - 380. MEETING ABSTRACT.

Hessheimer A, Coll E, Valdivieso A, Gomez M, Santoyo J, Ramirez P, et al. Superior outcomes using normothermic regional perfusion in cDCD liver transplantation. Transplantation. 2018; 102(5): 6 - 6. MEETING ABSTRACT.

Stigliano S, Waldthaler A, Martinez-Moneo E, Lionetto L, Robinson S, Malvik M, et al. Vitamins D and K as Factors Associated with Osteopathy in Chronic Pancreatitis: A Prospective Multicentre Study (P-BONE Study). Clin Transl Gastroenterol. 2018; 9: 197. FI: 4,621(Q1). DOI: 10.1038/s41424-018-0066-8.

Agüero F, Forner A, Valdivieso A, Blanes M, Barcena R, Manzardo C, et al. Human immunodeficiency virus-infected liver transplant recipients with incidental hepatocellular carcinoma: A prospective multicenter nationwide cohort study. Liver Transplant. 2017;23:645651. FI:3,910(Q1). DOI:10.1002/lt.24741.

Alonso-Calderón E, Pérez-González C, Prieto-Calvo M, Marquina-Tobalina T. Emphysematous pancreatitis. Fulminant course. Cir Esp. 2017;95:611. FI:1,276(Q3). DOI:10.1016/j.ciresp.2016.12.012. EDITORIAL MATERIAL

D'Avola D, Cuervas-Mons V, Martí J, Ortiz de Urbina J, Lladó L, Jimenez C, et al. Cardiovascular morbidity and mortality after liver transplantation: The protective role of mycophenolate mofetil. Liver Transplant. 2017;23:498-509. FI:3,910(Q1). DOI:10.1002/lt.24738.

Fernández Gómez-Cruzado L, Prieto Calvo M, Pérez González C, Larrea Oleaga J. Diverticulitis of the appendix as debut of appendicular cystadenoma and carcinoid tumor. Rev Esp Enferm Dig. 2017;109:145-6. FI:1,401(Q4).

Gastaca M, Sapisochin G. Mixed hepatocellular and cholangiocarcinoma: the difficulty of finding the right answer. HPB. 2017;19:558. FI:3,290(Q1). DOI:10.1016/j.hpb.2017.01.007.

Londono MC, Manzardo C, Del Campo S, Castells L, Aguilera V, Fernandez JR, et al. Interferon-free therapy is effective and safe for hepatitis C recurrence in liver transplant hepatitis C virus/human immunodeficiency virus coinfected recipients: a case-control study. J Hepatol. 2017;66:189. FI:12,486(Q1). DOI:10.1016/S0168-8278(17)30669-4. ABSTRACT

Pascasio JM, Vinaixa C, Ferrer MT, Colmenero J, Rubin A, Castells L, et al. Clinical outcomes of patients delisted from thewaiting list of liver; transplantation after interferon-free antiviral therapy. J Hepatol. 2017;66:186. FI:12,486(Q1). DOI:10.1016/S0168-8278(17)30661-X. ABSTRACT

Pascasio JM, Vinaixa C, Ferrer MT, Colmenero J, Rubin A, Castells L, et al. Clinical outcomes of patients undergoing antiviral therapy while; awaiting liver transplantation. J Hepatol. 2017;67:1168-76. FI:12,486(Q1). DOI:10.1016/j.jhep.2017.08.008.

Perelló C, Carrión JA, Ruiz-Antorán B, Crespo J, Turnes J, Llaneras J, et al. Effectiveness and safety of ombitasvir, paritaprevir, ritonavir +/- dasabuvir +/- ribavirin: An early access programme for Spanish patients; with genotype 1/4 chronic hepatitis C virus infection. J Viral Hepatitis. 2017;24:26-37. FI:4,122(Q1). DOI:10.1111/jvh.12637.

Prieto M, Gastaca M, Valdivieso A, de Urbina JO. Does Low Hepatic Artery Flow Increase Rate of Biliary Strictures in Deceased Donor Liver Transplantation? Reply Transplantation. 2017;101:311. FI:3,678(Q1). DOI:10.1097/TP.0000000000001855.

Prieto M, Gastaca M, Valdivieso A, de Urbina JO. Does Low Hepatic Artery Flow Increase Rate of Biliary Strictures in Deceased Donor Liver Transplantation? Transplantation. 2017;101:311. FI:3,678(Q1). DOI:10.1097/TP.0000000000001854.

Salcedo M, Prieto M, Castells L, Pascasio JM, Alvarez JLM, Fernandez I, et al. Efficacy and safety of daclatasvir-based antiviral therapy in hepatitis C virus recurrence after liver transplantation. Role of cirrhosis and genotype 3. A multicenter cohort study. Transpl Int. 2017;30:1041-50. FI:3,079(Q1). DOI:10.1111/tri.12999.

Arteagoitia MI, Ramos E, Santamaría G, Álvarez J, Barbier L, Santamaría J. Survey of spanish dentists on the prescription of antibiotics and antiseptics in surgery for impacted lower third molars. Med Oral Patol Oral Cir Bucal. 2016;21:e82-7. FI:1,156(Q3). DOI:10.4317/medoral.20669.

Tartaglione G, Stoeckli SJ, de Bree R, Schilling C, Flach GB, Bakholdt V, et al. Sentinel Node in Oral Cancer: The Nuclear Medicine Aspects. A Survey from the Sentinel European Node Trial. Clin Nucl Med. 2016;41:534-42. FI:3,640(Q1). DOI:10.1097/RLU.0000000000001241.

Brizuela-Velasco A, Diéguez-Pereira M, Álvarez-Arenal Á, Chávarri-Prado D, Solaberrieta E, Fernández-González FJ, et al. Fracture Resistance of Monolithic High Translucency Zirconia Implant-Supported Crowns. Implant Dent. 2016;25:624-8. FI:1,107(Q3). DOI:10.1097/ID.0000000000000439.

Arteagoitia MI, Barbier L, Santamaría J, Santamaría G, Ramos E. Efficacy of amoxicillin and amoxicillin/clavulanic acid in the prevention of infection and dry socket after third molar extraction. A systematic review and meta-analysis.Med Oral Patol Oral Cir Bucal. 2016;21:e494-504. FI:1,156(Q3). DOI:10.4317/medoral.21139.

Ramos E, Santamaría J, Santamaría G, Barbier L, Arteagoitia I. Do systemic antibiotics prevent dry socket and infection after third molar extraction? A systematic review and meta-analysis. Oral Surg Oral Med Oral Pathol Oral Radiol. 2016;122:403-25. FI:1,416(Q3). DOI:10.1016/j.oooo.2016.04.016.

Brunso J, Franco M, Constantinescu T, Barbier L, Santamaría JA, Alvarez J. Custom-Machined Miniplates and Bone-Supported Guides for Orthognathic Surgery: A New Surgical Procedure. J Oral Maxillofac Surg. 2016;74:1061.e1-1061.e12. FI:1,916(Q2). DOI:10.1016/j.joms.2016.01.016.

Arteagoitia I, Ramos E, Santamaria G, Barbier L, Alvarez J, Santamaria J. Amoxicillin/clavulanic acid 2000/125 mg to prevent complications due to infection following completely bone-impacted lower third molar removal: a clinical trial. Or Surg Or Med Or Pa. 2015;119:8-16. FI:1,262(Q3). DOI:10.1016/j.oooo.2014.08.014.

Brizuela-Velasco A, Álvarez-Arenal Á, Ellakuria-Echevarria J, del Río-Highsmith J, Santamaría-Arrieta G, Martín-Blanco N. Influence of Articulating Paper Thickness on Occlusal Contacts Registration: A Preliminary Report. Int J Prosthodont. 2015;28: 360-362. FI:1,487(Q2).

Cacicedo J, Fernandez I, del Hoyo O, Dolado A, Gomez-Suarez J, Hortelano E, et al. Should PET/CT be implemented in the routine imaging work-up of locally advanced head and neck squamous cell carcinoma? A prospective analysis. Eur J Nucl Med Mol I. 2015;42:1378-1389. FI:5,537(Q1). DOI:10.1007/s00259-015-3071-0.
 

Bernal-Bellido C, Prieto Castillo M, Ortiz de Urbina J, Serrano T, Poyato A, Otero A, et al. Multicenter Study of Elective Liver Retransplantation in Spain. Liver Transplant. 2014;20:189. FI: 4,241(Q1)

Briceño J, Cruz-Ramírez M, Prieto M, Navasa M, Ortiz de Urbina J, Orti R, et al. Use of artificial intelligence as an innovative donor-recipient matching model for liver transplantation: Results from a multicenter Spanish study. J Hepatol. 2014;61:1020-8. FI: 11,336(Q1)

Bustamante J, Klintman D, Kriese S, Munoz Tornero M, Cadden I, McDougall N, et al. Liver Transplantation for Autoimmune Hepatitis with DCD Donors. Liver Transplant. 2014;20:190. FI: 4,241(Q1)

Buti M, Morillas RM, Pérez J, Prieto M, Solà R, Palau A, et al; ORIENTE-2 study group. Entecavir has high efficacy and safety in Caucasian patients with chronic hepatitis B and co-morbidities. J Viral Hepatitis. 2014;21:38-9. FI: 3,909(Q1)

Fabregat J, Bilbao I, Salcedo M, Gomez MA, Jimenez C, Castroagudin J, et al. Everolimus Treatment in Liver Transplantation. A Spanish Multicentre Cohort. Liver Transplant. 2014;20:246. FI: 4,241(Q1)

Marquina T, Fondevila JJ, Prieto M, Valdivieso A. Giant hydatid cyst. Nenuphar sign. Cir Esp. 2013;91:605. FI: 0,871(Q3)

Sapisochin G, Rodriguez de Lope C, Gastaca M, Ortiz  de Urbina J, Lopez  Andujar R, Palacios F, et al. Intrahepatic cholangiocarcinoma or mixed hepatocellular- cholangiocarcinoma in patients undergoing liver transplantation. A spanish matched cohort multicenter study. Transpl Int. 2013;26:4. FI: 3,155(Q1)

Prieto M, Gastaca M, Agirre L, Colina A. Randomized clinical trial of self-gripping mesh versus sutured mesh for Lichtenstein hernia repair (Br J Surg 2013; 100: 474-481). Br J Surg. 2013;100:1538. FI: 4,839(Q1)

Chizhik A, Zhukov A, Gonzalez J. Magnetic properties of sub-micrometric Fe-rich wires.Thin Solid Films. 2013;543:130-2. FI: 1,604(Q2)

Gastaca M. Temporary intraoperative porto-caval shunt: A more complete set of data is needed. Transpl Int. 2013;26:81-2. FI: 3,155(Q1)

Valdivieso N, Oteo I, Valdivieso A, Lukas JC, Leal N, Gastaca M, et al. Tacrolimus dose individualization in ``de novo'' patients after 10 years of experience in liver transplantation: pharmacokinetic considerations and patient pathophysiology. Int J Clin Pharmacol Ther. 2013;51:606-14. FI: 1,200(Q4)

Gastaca M, Andres V, Ruiz P, Ventoso A, de Urbina JO. T-tube or No T-tube in Cadaveric Orthotopic Liver Transplantation: The Type of Tube Really Matters. Ann Surg. 2013; -0. FI: 6,329(Q1)

Le Treut YP, Grégoire E, Klempnauer J, Belghiti J, Jouve E, Lerut J, et al; For ELITA. Liver Transplantation for Neuroendocrine Tumors in Europe-Results and Trends in Patient Selection A 213-Case European Liver Transplant Registry Study. Ann Surg. 2013;257:807-15. FI: 6,329(Q1)

Gastaca M, Aguero F, Peter S, Paolo G, Jueergen R, Kosh A, et al. FIPSE NIH HIVTR NEAT023. Liver Retransplantation in HIV-Infected Patients: A Multicenter and Multinational Cohort Study. Am J Transplant. 2013;13:146. FI: 6,192(Q1). (Meeting Abstract).

Rodriguez-Lope C, Sapisochin G, Gastaca M, Ortiz de Urbina J, Lopez-Andujar R, Palacios F,  et al. Intrahepatic cholangiocarcinoma (I-CC) or mixed hepatocellular-cholangiocarcinoma (HCC-CC) in patients undergoing liver transplantation. A spanish case control multicenter study. J Hepatol. 2013;58:114-5. FI: 9,858(Q1). (Meeting Abstract).

Charco R, Sapisochin G, Rodriguez-Lope C, Gastaca M, Ortiz de Urbina J, Lopez-Andujar R, et al. Intrahepatic Cholangiocarcinoma (I-CC) or Mixed Hepatocellular-Cholangiocarcinoma (HCC-CC) in Patients Undergoing Liver Transplantation (LT). Am J Transplant. 2013;13:244. FI: 6,192(Q1). (Meeting Abstract).

Sukhostavets OV, Gonzalez J, Guslienko KY. Multipole magnetostatic interactions and collective vortex excitations in dot pairs, chains, and two-dimensional arrays. Phys Rev B. 2013;87:094402. FI: 3,767(Q1)

Oteo I, Lukas JC, Leal N, Suarez E, Valdivieso A, Gastaca M, et al. Tacrolimus pharmacokinetics in the early post-liver transplantation period and clinical applicability via Bayesian prediction. Eur J Clin Pharmacol. 2013;69:65-74. FI: 2,741(Q2)

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